Protection against atherogenesis with the polymer drag-reducing agent Separan AP-30.

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Protection against atherogenesis with the polymer drag-reducing agent Separan AP-30.

The inhibitory effect of Separan AP-30, an anionic polyacrylamide, on atherosclerotic plaque formation in aortas of rabbits on a high (2%) cholesterol diet was tested over a period extending from 37 to 170 days. Atherogenesis was quantified morphometrically by application of a computer-assisted image analysis of histologic cross sections of the aorta. The area of vessel wall-atheroma interface,...

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ژورنال

عنوان ژورنال: Circulation

سال: 1987

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.75.3.627